All-In Zoey

The main goal is to max out the Runic Axe with Heirloom, Inscription of Glory, Inscription Of the Elders, Ancient Power and Scriptweaver. Using Will to Survive and Strong-Armed you can do All-In big attacks with the Axe and one-shot / get clues / heal etc. Normally it's a huge risk to put all eggs into one bucket risking all the Axe charges with one attack, but with those cards you can make sure you will succeed.

But what to do while your Axe is recharging? Well, you have Blessed Blade with Occult Reliquary. It seems like that's a lot of XP, but with Down the Rabbit Hole and only 3 new cards along the way, you will have a big chunk of cheaper upgrades.

It's also resource heavy strategy, so that's why you can put Ever Vigilant, Kicking the Hornet's Nest and On the Hunt into Stick to the Plan. Two of those cards can also be used to make sure you have something to attack when your Axe is fully recharged. The most important upgrades are Backpacks and Runic Axe. I suppose this build sucks early game, but with some XP that should change